Installation

Download the repository

Download the SANPRO programs from the GitHub repository located at
https://github.com/CNIC-Proteomics/SANPRO.

Next, decompress the zip file.

You need to install the Python programming language and the following packages. To install these packages, you can use the pip module in Python:

pip install -r python_requirements.txt

The "get_appris" service requires the APPRIS data files. To obtain these files for a specific species, you need to execute the following bash script:

./create_appris_dbs.sh

This bash script contains the following programs:

The following script downloads annotations for the APPRIS methods that locate annotations in specific regions of the protein:

python download_appris.py    -s human     -o test/appris       -vv  &> logs/download_apprishuman.log

Additionally, to convert the method annotations in GTF format to another GTF format that references the protein region, you can use:

python  convert_appris.py  -ia "test/appris/*.gtf"  -iu "test/human_202306.uniprot.tsv" -o "test/appris/human_202306.appris.gtf"