A curated course on Geospatial Data Science with Python. It focuses on the key concepts of G.I.S Programming in a simplified manner and various geospatial processes using Python. The tutorials were used in mentoring others on Geospatial Data Science including the UON GESA - Spatial Analysis Hub and Students from Dedan Kimathi University of Technology, JKUAT, among others. Geospatial personnel interested on the topics might also gain insight on various key issues in Python programming with G.I.S