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Possible to download ARO with mechanisms? #13

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merytouceda opened this issue Feb 1, 2024 · 1 comment
Open

Possible to download ARO with mechanisms? #13

merytouceda opened this issue Feb 1, 2024 · 1 comment
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@merytouceda
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Hi!

I was wondering if there is a way to download a table that contains the accession number or name of the gene and the mechanism of resistance. When I download the aro.tsv from the CARD site (https://card.mcmaster.ca/download) I only get the description, but not the broader classifications of each gene.

Thanks!

@arpcard arpcard self-assigned this Feb 14, 2024
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arpcard commented Feb 14, 2024

@merytouceda maybe the file aro_index.tsv in the Download CARD Data section will help:

cat aro_index.tsv | head -10
ARO Accession	CVTERM ID	Model Sequence ID	Model ID	Model Name	ARO Name	Protein Accession	DNA Accession	AMR Gene Family	Drug Class	Resistance Mechanism	CARD Short Name
ARO:3005099	43314	6143	3831	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A)	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A)	AAB60941.1	AF002716.1	Erm 23S ribosomal RNA methyltransferase	lincosamide antibiotic;macrolide antibiotic;streptogramin antibiotic	antibiotic target alteration	Spyo_ErmA_MLSb
ARO:3002523	38923	8144	1781	AAC(2')-Ia	AAC(2')-Ia	AAA03550.1	L06156.2	AAC(2')	aminoglycoside antibiotic	antibiotic inactivation	AAC(2')-Ia
ARO:3002524	38924	85	746	AAC(2')-Ib	AAC(2')-Ib	AAC44793.1	U41471.1	AAC(2')	aminoglycoside antibiotic	antibiotic inactivation	AAC(2')-Ib
ARO:3002525	38925	4719	1246	AAC(2')-Ic	AAC(2')-Ic	CCP42991.1	AL123456.3	AAC(2')	aminoglycoside antibiotic	antibiotic inactivation	AAC(2')-Ic
ARO:3002526	38926	228	1415	AAC(2')-Id	AAC(2')-Id	AAB41701.1	U72743.1	AAC(2')	aminoglycoside antibiotic	antibiotic inactivation	AAC(2')-Id
ARO:3002527	38927	5510	2832	AAC(2')-Ie	AAC(2')-Ie	CAC32082.1	AL583926.1	AAC(2')	aminoglycoside antibiotic	antibiotic inactivation	AAC(2')-Ie
ARO:3004628	42613	5361	3327	AAC(2')-IIa	AAC(2')-IIa	BAM16262.1	AB669090.1	AAC(2')	aminoglycoside antibiotic	antibiotic inactivation	AAC(2')-IIa
ARO:3003988	40870	3860	2524	AAC(2')-IIb	AAC(2')-IIb	APB03221.1	KX531051.1	AAC(2')	aminoglycoside antibiotic	antibiotic inactivation	AAC(2')-IIb
ARO:3002528	38928	8360	39	AAC(3)-Ia	AAC(3)-Ia	AAG15269.1	U12338.3	AAC(3)	aminoglycoside antibiotic	antibiotic inactivation	AAC(3)-Ia

@arpcard arpcard assigned merytouceda and unassigned arpcard Feb 14, 2024
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