diff --git a/codegen/smithy-aws-typescript-codegen/src/main/java/software/amazon/smithy/aws/typescript/codegen/AwsProtocolUtils.java b/codegen/smithy-aws-typescript-codegen/src/main/java/software/amazon/smithy/aws/typescript/codegen/AwsProtocolUtils.java
index c4c9eec9cc0dc..12a86e8c65015 100644
--- a/codegen/smithy-aws-typescript-codegen/src/main/java/software/amazon/smithy/aws/typescript/codegen/AwsProtocolUtils.java
+++ b/codegen/smithy-aws-typescript-codegen/src/main/java/software/amazon/smithy/aws/typescript/codegen/AwsProtocolUtils.java
@@ -305,44 +305,17 @@ private static boolean filterProtocolTests(
             HttpMessageTestCase testCase,
             TypeScriptSettings settings
     ) {
-        // TODO: Remove when requestCompression has been implemented.
-        if (testCase.getId().startsWith("SDKAppliedContentEncoding_")
-            || testCase.getId().startsWith("SDKAppendsGzipAndIgnoresHttpProvidedEncoding_")
-            || testCase.getId().startsWith("SDKAppendedGzipAfterProvidedEncoding_")) {
-            return true;
-        }
-
         // TODO: Remove when upstream tests update to serialize empty headers.
         if (testCase.getId().contains("NullAndEmptyHeaders")) {
             return true;
         }
 
-        if (testCase.getTags().contains("defaults")) {
-            return true;
-        }
-
-        // TODO: remove when there's a decision on separator to use
-        // https://github.com/awslabs/smithy/issues/1014
-        if (testCase.getId().equals("RestJsonInputAndOutputWithQuotedStringHeaders")) {
-            return true;
-        }
-
-        // TODO: implementation change pending.
-        List<String> extraUnionKey = Arrays.asList(
-            "RestXmlHttpPayloadWithUnsetUnion",
-            "RestJsonHttpPayloadWithUnsetUnion"
-        );
-        if (extraUnionKey.contains(testCase.getId())) {
-            return true;
-        }
-
         // TODO: remove when Glacier AccountID hyphen customization is implemented: SMITHY-2614
         if (testCase.getId().equals("GlacierAccountId")) {
             return true;
         }
 
-        // ToDo: https://github.com/aws/aws-sdk-js-v3/issues/6246
-        if (testCase.getId().equals("RestJsonMustSupportParametersInContentType")) {
+        if (testCase.getTags().contains("defaults")) {
             return true;
         }
 
diff --git a/private/aws-protocoltests-ec2/test/functional/ec2query.spec.ts b/private/aws-protocoltests-ec2/test/functional/ec2query.spec.ts
index 99e8e415705f6..74ec6870cb556 100644
--- a/private/aws-protocoltests-ec2/test/functional/ec2query.spec.ts
+++ b/private/aws-protocoltests-ec2/test/functional/ec2query.spec.ts
@@ -835,7 +835,7 @@ it("Ec2QueryNoInputAndOutput:Response", async () => {
 /**
  * Compression algorithm encoding is appended to the Content-Encoding header.
  */
-it.skip("SDKAppliedContentEncoding_ec2Query:Request", async () => {
+it("SDKAppliedContentEncoding_ec2Query:Request", async () => {
   const client = new EC2ProtocolClient({
     ...clientParams,
     requestHandler: new RequestSerializationTestHandler(),
@@ -868,7 +868,7 @@ it.skip("SDKAppliedContentEncoding_ec2Query:Request", async () => {
  * traits are ignored in the ec2Query protocol.
  *
  */
-it.skip("SDKAppendsGzipAndIgnoresHttpProvidedEncoding_ec2Query:Request", async () => {
+it("SDKAppendsGzipAndIgnoresHttpProvidedEncoding_ec2Query:Request", async () => {
   const client = new EC2ProtocolClient({
     ...clientParams,
     requestHandler: new RequestSerializationTestHandler(),
diff --git a/private/aws-protocoltests-json-10/test/functional/awsjson1_0.spec.ts b/private/aws-protocoltests-json-10/test/functional/awsjson1_0.spec.ts
index 029b8bccf6955..a868bb62a1398 100644
--- a/private/aws-protocoltests-json-10/test/functional/awsjson1_0.spec.ts
+++ b/private/aws-protocoltests-json-10/test/functional/awsjson1_0.spec.ts
@@ -2751,7 +2751,7 @@ it.skip("AwsJson10ClientErrorCorrectsWhenServerFailsToSerializeRequiredValues:Re
 /**
  * Compression algorithm encoding is appended to the Content-Encoding header.
  */
-it.skip("SDKAppliedContentEncoding_awsJson1_0:Request", async () => {
+it("SDKAppliedContentEncoding_awsJson1_0:Request", async () => {
   const client = new JSONRPC10Client({
     ...clientParams,
     requestHandler: new RequestSerializationTestHandler(),
@@ -2784,7 +2784,7 @@ it.skip("SDKAppliedContentEncoding_awsJson1_0:Request", async () => {
  * traits are ignored in the awsJson1_0 protocol.
  *
  */
-it.skip("SDKAppendsGzipAndIgnoresHttpProvidedEncoding_awsJson1_0:Request", async () => {
+it("SDKAppendsGzipAndIgnoresHttpProvidedEncoding_awsJson1_0:Request", async () => {
   const client = new JSONRPC10Client({
     ...clientParams,
     requestHandler: new RequestSerializationTestHandler(),
diff --git a/private/aws-protocoltests-json/test/functional/awsjson1_1.spec.ts b/private/aws-protocoltests-json/test/functional/awsjson1_1.spec.ts
index 4b026aaa6af3e..d34e81ffd364d 100644
--- a/private/aws-protocoltests-json/test/functional/awsjson1_1.spec.ts
+++ b/private/aws-protocoltests-json/test/functional/awsjson1_1.spec.ts
@@ -4410,7 +4410,7 @@ it("PutAndGetInlineDocumentsInput:Response", async () => {
 /**
  * Compression algorithm encoding is appended to the Content-Encoding header.
  */
-it.skip("SDKAppliedContentEncoding_awsJson1_1:Request", async () => {
+it("SDKAppliedContentEncoding_awsJson1_1:Request", async () => {
   const client = new JsonProtocolClient({
     ...clientParams,
     requestHandler: new RequestSerializationTestHandler(),
@@ -4443,7 +4443,7 @@ it.skip("SDKAppliedContentEncoding_awsJson1_1:Request", async () => {
  * traits are ignored in the awsJson1_1 protocol.
  *
  */
-it.skip("SDKAppendsGzipAndIgnoresHttpProvidedEncoding_awsJson1_1:Request", async () => {
+it("SDKAppendsGzipAndIgnoresHttpProvidedEncoding_awsJson1_1:Request", async () => {
   const client = new JsonProtocolClient({
     ...clientParams,
     requestHandler: new RequestSerializationTestHandler(),
diff --git a/private/aws-protocoltests-query/test/functional/awsquery.spec.ts b/private/aws-protocoltests-query/test/functional/awsquery.spec.ts
index f9d762e525dc5..b7c25a4c73211 100644
--- a/private/aws-protocoltests-query/test/functional/awsquery.spec.ts
+++ b/private/aws-protocoltests-query/test/functional/awsquery.spec.ts
@@ -1088,7 +1088,7 @@ it("QueryNoInputAndOutput:Response", async () => {
 /**
  * Compression algorithm encoding is appended to the Content-Encoding header.
  */
-it.skip("SDKAppliedContentEncoding_awsQuery:Request", async () => {
+it("SDKAppliedContentEncoding_awsQuery:Request", async () => {
   const client = new QueryProtocolClient({
     ...clientParams,
     requestHandler: new RequestSerializationTestHandler(),
@@ -1121,7 +1121,7 @@ it.skip("SDKAppliedContentEncoding_awsQuery:Request", async () => {
  * traits are ignored in the awsQuery protocol.
  *
  */
-it.skip("SDKAppendsGzipAndIgnoresHttpProvidedEncoding_awsQuery:Request", async () => {
+it("SDKAppendsGzipAndIgnoresHttpProvidedEncoding_awsQuery:Request", async () => {
   const client = new QueryProtocolClient({
     ...clientParams,
     requestHandler: new RequestSerializationTestHandler(),
diff --git a/private/aws-protocoltests-restjson/test/functional/restjson1.spec.ts b/private/aws-protocoltests-restjson/test/functional/restjson1.spec.ts
index 57b6c3b36315a..f05a1a5f0fabf 100644
--- a/private/aws-protocoltests-restjson/test/functional/restjson1.spec.ts
+++ b/private/aws-protocoltests-restjson/test/functional/restjson1.spec.ts
@@ -2695,7 +2695,7 @@ it("RestJsonHttpPayloadWithUnion:Request", async () => {
 /**
  * No payload is sent if the union has no value.
  */
-it.skip("RestJsonHttpPayloadWithUnsetUnion:Request", async () => {
+it("RestJsonHttpPayloadWithUnsetUnion:Request", async () => {
   const client = new RestJsonProtocolClient({
     ...clientParams,
     requestHandler: new RequestSerializationTestHandler(),
@@ -2764,7 +2764,7 @@ it("RestJsonHttpPayloadWithUnion:Response", async () => {
 /**
  * No payload is sent if the union has no value.
  */
-it.skip("RestJsonHttpPayloadWithUnsetUnion:Response", async () => {
+it("RestJsonHttpPayloadWithUnsetUnion:Response", async () => {
   const client = new RestJsonProtocolClient({
     ...clientParams,
     requestHandler: new ResponseDeserializationTestHandler(
@@ -3440,7 +3440,7 @@ it("RestJsonInputAndOutputWithStringHeaders:Request", async () => {
 /**
  * Tests requests with string list header bindings that require quoting
  */
-it.skip("RestJsonInputAndOutputWithQuotedStringHeaders:Request", async () => {
+it("RestJsonInputAndOutputWithQuotedStringHeaders:Request", async () => {
   const client = new RestJsonProtocolClient({
     ...clientParams,
     requestHandler: new RequestSerializationTestHandler(),
@@ -3804,7 +3804,7 @@ it("RestJsonInputAndOutputWithStringHeaders:Response", async () => {
 /**
  * Tests responses with string list header bindings that require quoting
  */
-it.skip("RestJsonInputAndOutputWithQuotedStringHeaders:Response", async () => {
+it("RestJsonInputAndOutputWithQuotedStringHeaders:Response", async () => {
   const client = new RestJsonProtocolClient({
     ...clientParams,
     requestHandler: new ResponseDeserializationTestHandler(true, 200, {
@@ -7853,7 +7853,7 @@ it("PostUnionWithJsonNameResponse3:Response", async () => {
 /**
  * Compression algorithm encoding is appended to the Content-Encoding header.
  */
-it.skip("SDKAppliedContentEncoding_restJson1:Request", async () => {
+it("SDKAppliedContentEncoding_restJson1:Request", async () => {
   const client = new RestJsonProtocolClient({
     ...clientParams,
     requestHandler: new RequestSerializationTestHandler(),
@@ -7886,7 +7886,7 @@ it.skip("SDKAppliedContentEncoding_restJson1:Request", async () => {
  * request compression encoding from the HTTP binding.
  *
  */
-it.skip("SDKAppendedGzipAfterProvidedEncoding_restJson1:Request", async () => {
+it("SDKAppendedGzipAfterProvidedEncoding_restJson1:Request", async () => {
   const client = new RestJsonProtocolClient({
     ...clientParams,
     requestHandler: new RequestSerializationTestHandler(),
@@ -7910,7 +7910,7 @@ it.skip("SDKAppendedGzipAfterProvidedEncoding_restJson1:Request", async () => {
     expect(r.path).toBe("/requestcompression/putcontentwithencoding");
 
     expect(r.headers["content-encoding"]).toBeDefined();
-    expect(r.headers["content-encoding"]).toBe("custom, gzip");
+    expect(r.headers["content-encoding"].replaceAll(", ", ",")).toBe("custom, gzip".replaceAll(", ", ","));
   }
 });
 
diff --git a/private/aws-protocoltests-restxml/test/functional/restxml.spec.ts b/private/aws-protocoltests-restxml/test/functional/restxml.spec.ts
index e18f9ad96d5e9..88578f44cd7a5 100644
--- a/private/aws-protocoltests-restxml/test/functional/restxml.spec.ts
+++ b/private/aws-protocoltests-restxml/test/functional/restxml.spec.ts
@@ -1923,7 +1923,7 @@ it("RestXmlHttpPayloadWithUnion:Request", async () => {
 /**
  * No payload is sent if the union has no value.
  */
-it.skip("RestXmlHttpPayloadWithUnsetUnion:Request", async () => {
+it("RestXmlHttpPayloadWithUnsetUnion:Request", async () => {
   const client = new RestXmlProtocolClient({
     ...clientParams,
     requestHandler: new RequestSerializationTestHandler(),
@@ -1992,7 +1992,7 @@ it("RestXmlHttpPayloadWithUnion:Response", async () => {
 /**
  * No payload is sent if the union has no value.
  */
-it.skip("RestXmlHttpPayloadWithUnsetUnion:Response", async () => {
+it("RestXmlHttpPayloadWithUnsetUnion:Response", async () => {
   const client = new RestXmlProtocolClient({
     ...clientParams,
     requestHandler: new ResponseDeserializationTestHandler(
@@ -3831,7 +3831,7 @@ it("RestXmlSerializesEmptyString:Request", async () => {
 /**
  * Compression algorithm encoding is appended to the Content-Encoding header.
  */
-it.skip("SDKAppliedContentEncoding_restXml:Request", async () => {
+it("SDKAppliedContentEncoding_restXml:Request", async () => {
   const client = new RestXmlProtocolClient({
     ...clientParams,
     requestHandler: new RequestSerializationTestHandler(),
@@ -3864,7 +3864,7 @@ it.skip("SDKAppliedContentEncoding_restXml:Request", async () => {
  * request compression encoding from the HTTP binding.
  *
  */
-it.skip("SDKAppendedGzipAfterProvidedEncoding_restXml:Request", async () => {
+it("SDKAppendedGzipAfterProvidedEncoding_restXml:Request", async () => {
   const client = new RestXmlProtocolClient({
     ...clientParams,
     requestHandler: new RequestSerializationTestHandler(),
@@ -3888,7 +3888,7 @@ it.skip("SDKAppendedGzipAfterProvidedEncoding_restXml:Request", async () => {
     expect(r.path).toBe("/requestcompression/putcontentwithencoding");
 
     expect(r.headers["content-encoding"]).toBeDefined();
-    expect(r.headers["content-encoding"]).toBe("custom, gzip");
+    expect(r.headers["content-encoding"].replaceAll(", ", ",")).toBe("custom, gzip".replaceAll(", ", ","));
   }
 });
 
diff --git a/private/aws-restjson-server/test/functional/restjson1.spec.ts b/private/aws-restjson-server/test/functional/restjson1.spec.ts
index 27611325738e0..c16429f07ec80 100644
--- a/private/aws-restjson-server/test/functional/restjson1.spec.ts
+++ b/private/aws-restjson-server/test/functional/restjson1.spec.ts
@@ -972,7 +972,7 @@ it("RestJsonConstantQueryString:ServerRequest", async () => {
 /**
  * A server should ignore parameters added to the content type
  */
-it.skip("RestJsonMustSupportParametersInContentType:ServerRequest", async () => {
+it("RestJsonMustSupportParametersInContentType:ServerRequest", async () => {
   const testFunction = jest.fn();
   testFunction.mockReturnValue(Promise.resolve({}));
   const testService: Partial<RestJsonService<{}>> = {
@@ -3089,7 +3089,7 @@ it("RestJsonHttpPayloadWithUnion:ServerRequest", async () => {
 /**
  * No payload is sent if the union has no value.
  */
-it.skip("RestJsonHttpPayloadWithUnsetUnion:ServerRequest", async () => {
+it("RestJsonHttpPayloadWithUnsetUnion:ServerRequest", async () => {
   const testFunction = jest.fn();
   testFunction.mockReturnValue(Promise.resolve({}));
   const testService: Partial<RestJsonService<{}>> = {
@@ -3181,7 +3181,7 @@ it("RestJsonHttpPayloadWithUnion:ServerResponse", async () => {
 /**
  * No payload is sent if the union has no value.
  */
-it.skip("RestJsonHttpPayloadWithUnsetUnion:ServerResponse", async () => {
+it("RestJsonHttpPayloadWithUnsetUnion:ServerResponse", async () => {
   class TestService implements Partial<RestJsonService<{}>> {
     HttpPayloadWithUnion(input: any, ctx: {}): Promise<HttpPayloadWithUnionServerOutput> {
       const response = {} as any;
@@ -4183,7 +4183,7 @@ it("RestJsonInputAndOutputWithStringHeaders:ServerRequest", async () => {
 /**
  * Tests requests with string list header bindings that require quoting
  */
-it.skip("RestJsonInputAndOutputWithQuotedStringHeaders:ServerRequest", async () => {
+it("RestJsonInputAndOutputWithQuotedStringHeaders:ServerRequest", async () => {
   const testFunction = jest.fn();
   testFunction.mockReturnValue(Promise.resolve({}));
   const testService: Partial<RestJsonService<{}>> = {
@@ -4661,7 +4661,7 @@ it("RestJsonInputAndOutputWithStringHeaders:ServerResponse", async () => {
 /**
  * Tests responses with string list header bindings that require quoting
  */
-it.skip("RestJsonInputAndOutputWithQuotedStringHeaders:ServerResponse", async () => {
+it("RestJsonInputAndOutputWithQuotedStringHeaders:ServerResponse", async () => {
   class TestService implements Partial<RestJsonService<{}>> {
     InputAndOutputWithHeaders(input: any, ctx: {}): Promise<InputAndOutputWithHeadersServerOutput> {
       const response = {
@@ -28798,7 +28798,7 @@ it("PostUnionWithJsonNameResponse3:ServerResponse", async () => {
 /**
  * Compression algorithm encoding is appended to the Content-Encoding header.
  */
-it.skip("SDKAppliedContentEncoding_restJson1:ServerRequest", async () => {
+it("SDKAppliedContentEncoding_restJson1:ServerRequest", async () => {
   const testFunction = jest.fn();
   testFunction.mockReturnValue(Promise.resolve({}));
   const testService: Partial<RestJsonService<{}>> = {
@@ -28844,7 +28844,7 @@ it.skip("SDKAppliedContentEncoding_restJson1:ServerRequest", async () => {
  * request compression encoding from the HTTP binding.
  *
  */
-it.skip("SDKAppendedGzipAfterProvidedEncoding_restJson1:ServerRequest", async () => {
+it("SDKAppendedGzipAfterProvidedEncoding_restJson1:ServerRequest", async () => {
   const testFunction = jest.fn();
   testFunction.mockReturnValue(Promise.resolve({}));
   const testService: Partial<RestJsonService<{}>> = {