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T_inhibition_induced_bursting.m
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%%%%%%%%%%%%%%%%%%%% (T) Inhibition-Induced Bursting %%%%%%%%%%%%%%%%%%%%
% These neurons can fire tonic bursts of spikes in response to a prolonged
% hyperpolarization.
clear variables;
a=-0.026; b=-1; c=-45; d=-2;
j=0.04; k=5; l=140;
r=false;
u=-63.8; % threshold value of the model neuron
w=b*u;
udot=[];
wdot=[];
grad_u=[];
grad_w=[];
tau = 0.5;
tspan = 0:tau:350;
for t=tspan
if (t < 50) || (t>250)
I=80;
else
I=75;
end
[u, w, du, dw, ud, wd] = izhikevich(a, b, c, d, j, k, l, u, w, I, tau, r);
udot(end+1)=ud;
wdot(end+1)=wd;
grad_u(end+1)=du;
grad_w(end+1)=dw;
end
% plot membrane potential
fig = figure;
plot(tspan,udot,[0 50 50 250 250 max(tspan)],-80+[0 0 -10 -10 0 0]);
axis([0 max(tspan) -90 30])
xlabel('time')
ylabel('membrane potential')
title('(T) inhibition induced bursting');
print(fig,'img/T_inhibition_induced_bursting_membrane_potential.png','-dpng')
% plot phase portrait
fig = figure;
hold on;
plot(udot,wdot)
quiver(udot,wdot,grad_u,grad_w,'r')
xlabel('membrane potential')
ylabel('recovery variable')
title('(T) inhibition induced bursting phase portrait');
print(fig,'img/T_inhibition_induced_bursting_phase_portrait.png','-dpng')