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@marcus1487 marcus1487 released this 20 Aug 21:42
· 269 commits to master since this release

This release includes a number of new features, optimizations and performance improvements:

  • Optimized read processing enabling reference anchored (highest quality) modified base calling the same speed as standalone guppy.
  • Live processing mode with all outputs enabled.
  • Support for (and new requirement of) Guppy 4.0+.
  • Basecall-anchored modified base calls now output in hts-spec unmapped BAM format (see specification here).
  • Optimized modified base data base scheme for smaller memory footprint, faster processing and faster aggregation.
  • Fixed bug for sequencing summary file when processing multi-FAST5 reads (Fixes #45).
  • Fixed bug where scaling factors were incorrect for signal mapping output in some settings (used for basecaller training).
  • Other various optimizations and minor bug fixes.