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This release includes a number of new features, optimizations and performance improvements:
- Optimized read processing enabling reference anchored (highest quality) modified base calling the same speed as standalone guppy.
- Live processing mode with all outputs enabled.
- Support for (and new requirement of) Guppy 4.0+.
- Basecall-anchored modified base calls now output in hts-spec unmapped BAM format (see specification here).
- Optimized modified base data base scheme for smaller memory footprint, faster processing and faster aggregation.
- Fixed bug for sequencing summary file when processing multi-FAST5 reads (Fixes #45).
- Fixed bug where scaling factors were incorrect for signal mapping output in some settings (used for basecaller training).
- Other various optimizations and minor bug fixes.