diff --git a/setup.py b/setup.py
index 87778684..e6950e28 100644
--- a/setup.py
+++ b/setup.py
@@ -75,7 +75,7 @@ def getVersionNumber():
     python_requires=">3.7",
     install_requires=[
         "gemmi>=0.5.5, <=0.6.5",
-        "pandas>=2.0.0, <=2.1.4",
+        "pandas>=2.0.0, <=2.2.1",
         "numpy",
         "scipy",
         "ipython",