diff --git a/package.json b/package.json
index 99cdc528b..e6c4aa9b7 100644
--- a/package.json
+++ b/package.json
@@ -83,7 +83,7 @@
     "flexsearch": "^0.7.43",
     "hls.js": "^1.5.3",
     "node-webvtt": "^1.9.4",
-    "openseadragon": "^2.4.2",
+    "openseadragon": "^4.1.1",
     "react": "^18.2.0",
     "react-dom": "^18.2.0",
     "react-error-boundary": "^4.0.12",
diff --git a/pnpm-lock.yaml b/pnpm-lock.yaml
index c7e95b4ca..dea02d51f 100644
--- a/pnpm-lock.yaml
+++ b/pnpm-lock.yaml
@@ -54,8 +54,8 @@ dependencies:
     specifier: ^1.9.4
     version: 1.9.4
   openseadragon:
-    specifier: ^2.4.2
-    version: 2.4.2
+    specifier: ^4.1.1
+    version: 4.1.1
   react:
     specifier: ^18.2.0
     version: 18.2.0
@@ -6798,8 +6798,8 @@ packages:
       mimic-fn: 4.0.0
     dev: true
 
-  /openseadragon@2.4.2:
-    resolution: {integrity: sha512-398KbZwRtOYA6OmeWRY4Q0737NTacQ9Q6whmr9Lp1MNQO3p0eBz5LIASRne+4gwequcSM1vcHcjfy3dIndQziw==}
+  /openseadragon@4.1.1:
+    resolution: {integrity: sha512-owU9gsasAcobLN+LM8lN58Xc2VDSDotY9mkrwS/NB6g9KX/PcusV4RZvhHng2RF/Q0pMziwldf62glwXoGnuzg==}
     dev: false
 
   /optionator@0.9.3:
diff --git a/src/components/Image/OSD/OSD.tsx b/src/components/Image/OSD/OSD.tsx
index 7eba65a90..b23fa5837 100644
--- a/src/components/Image/OSD/OSD.tsx
+++ b/src/components/Image/OSD/OSD.tsx
@@ -42,8 +42,11 @@ const OSD: React.FC<OSDProps> = ({
   }, [openSeadragon, openSeadragonCallback]);
 
   useEffect(() => {
-    if (uri !== osdUri) setOsdUri(uri);
-  }, [osdUri, uri]);
+    if (openSeadragon && uri !== osdUri) {
+      openSeadragon.forceRedraw();
+      setOsdUri(uri);
+    }
+  }, [openSeadragon, osdUri, uri]);
 
   useEffect(() => {
     if (osdUri && openSeadragon) {