Fix IMO error on motif input

clock.time

@@ -1 +1 @@
-Last updated at 16:15 10/09/2024
+Last updated at 10:20 07/01/2025 (dd/mm/aaaa)

navigation/IMF.py

@@ -248,13 +248,16 @@ def analyse(dna_sequence=None):
                     st.success(f"{TF_species} transcription factor {TF_name}")
                     with REcol2:
                         st.image(weblogo)
+                    isUIPAC = True
                     button = False
                     error_input_im = True
                 else:
+                    isUIPAC = False
                     button = True
                     error_input_im = False
                     st.error('Wrong JASPAR_ID')
             else:
+                isUIPAC = False
                 button = True
                 error_input_im = False
                 st.warning('Please enter a JASPAR_ID')
@@ -265,7 +268,6 @@ def analyse(dna_sequence=None):
             matrix_type = st.radio('🔹 :blue[**Step 2.2bis**] Matrix:', ('With FASTA sequences', 'With PWM'),
                                    label_visibility='collapsed')
         if matrix_type == 'With PWM':
-            isUIPAC = True
             with REcol2:
                 st.markdown("🔹 :blue[**Step 2.3**] Matrix:")
                 matrix_str = st.text_area("🔹 :blue[**Step 2.3**] Matrix:",
@@ -303,12 +305,14 @@ def analyse(dna_sequence=None):
                         weblogo.fig.savefig(logo, format='png')
                         logo.seek(0)
                         st.session_state['weblogo'] = logo
-
+                        isUIPAC = True
                         error_input_im = True
                     except Exception as e:
+                        isUIPAC = False
                         error_input_im = False
                         REcol2.error(e)
                 else:
+                    isUIPAC = False
                     error_input_im = False
                     REcol2.warning("Please input your PWM :)")
         else:
@@ -322,7 +326,6 @@ def analyse(dna_sequence=None):
                                                 label_visibility='collapsed')
                 st.session_state['individual_motif_save'] = individual_motif
                 individual_motif = individual_motif.upper()
-            isUIPAC = True
 
             try:
                 matrix, weblogo = IMO.individual_motif_pwm(individual_motif)
@@ -339,8 +342,10 @@ def analyse(dna_sequence=None):
                     weblogo.fig.savefig(logo, format='png')
                     logo.seek(0)
                     st.session_state['weblogo'] = logo
+                isUIPAC = True
                 error_input_im = True
             except Exception as e:
+                isUIPAC = False
                 error_input_im = False
                 REcol1.error(e)
 
@@ -357,33 +362,36 @@ def analyse(dna_sequence=None):
 
         IUPAC_code = ['A', 'T', 'G', 'C', 'R', 'Y', 'M', 'K', 'W', 'S', 'B', 'D', 'H', 'V', 'N', '-', '.']
 
-        if all(char in IUPAC_code for char in IUPAC):
-            isUIPAC = True
-            try:
-                matrix = IMO.generate_iupac_variants(IUPAC)
-                _, weblogo = IMO.individual_motif_pwm(matrix, "UIPAC")
+        if len(IUPAC) > 0:
+            if all(char in IUPAC_code for char in IUPAC):
+                isUIPAC = True
+                try:
+                    matrix = IMO.generate_iupac_variants(IUPAC)
+                    _, weblogo = IMO.individual_motif_pwm(matrix, "UIPAC")
 
-                matrix_str = ""
-                for base, values in matrix.items():
-                    values_str = " ".join([f"{val:.4f}" for val in values])
-                    matrix_str += f"{base} [ {values_str} ]\n"
+                    matrix_str = ""
+                    for base, values in matrix.items():
+                        values_str = " ".join([f"{val:.4f}" for val in values])
+                        matrix_str += f"{base} [ {values_str} ]\n"
 
-                with REcol2:
-                    matrix_text = st.text_area('PWM', value=matrix_str, height=125,
-                                               help='Copy to use later. Not editable.',
-                                               disabled=True)
+                    with REcol2:
+                        matrix_text = st.text_area('PWM', value=matrix_str, height=125,
+                                                   help='Copy to use later. Not editable.',
+                                                   disabled=True)
 
-                    st.pyplot(weblogo.fig)
-                    logo = io.BytesIO()
-                    weblogo.fig.savefig(logo, format='png')
-                    logo.seek(0)
-                    st.session_state['weblogo'] = logo
+                        st.pyplot(weblogo.fig)
+                        logo = io.BytesIO()
+                        weblogo.fig.savefig(logo, format='png')
+                        logo.seek(0)
+                        st.session_state['weblogo'] = logo
 
-                error_input_im = True
+                    error_input_im = True
 
-            except Exception as e:
-                error_input_im = False
-                REcol1.error(e)
+                except Exception as e:
+                    error_input_im = False
+                    REcol1.error(e)
+            else:
+                isUIPAC = False
         else:
             isUIPAC = False