Change the way to exclude regions in hmmratac
and fix the incorrect keep-duplicate
option
#689
Add this suggestion to a batch that can be applied as a single commit.
This suggestion is invalid because no changes were made to the code.
Suggestions cannot be applied while the pull request is closed.
Suggestions cannot be applied while viewing a subset of changes.
Only one suggestion per line can be applied in a batch.
Add this suggestion to a batch that can be applied as a single commit.
Applying suggestions on deleted lines is not supported.
You must change the existing code in this line in order to create a valid suggestion.
Outdated suggestions cannot be applied.
This suggestion has been applied or marked resolved.
Suggestions cannot be applied from pending reviews.
Suggestions cannot be applied on multi-line comments.
Suggestions cannot be applied while the pull request is queued to merge.
Suggestion cannot be applied right now. Please check back later.
hmmratac
. We will remove the aligned fragments located in the 'blacklist' regions before the EM step to estimate fragment lengths distributions and HMM step to learn and predict nucleosome states. The reason is discussed in Bug: No peaks detected in not-blacklisted regions when a blacklist is given to macs3 hmmratac #680. To implement this feature, we added theexclude
functions to PETrackI and PETrackII.hmmratac
option--keep-duplicate
had opposite effect previously as indicated by the name and description. It has been renamed as--remove-dup
to reflect the actual behavior.hmmratac
will not remove duplicated fragments unless this option is set.